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Biosensor-based assay of exosome biomarker for early diagnosis of cancer

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 157-175 doi: 10.1007/s11684-021-0884-z

Abstract: Therefore, early diagnosis of cancer is indispensable in the timely prevention and effective treatmentExosome has recently become an attractive cancer biomarker in noninvasive early diagnosis because ofof cancer.of cancer were evaluated.of cancer were discussed.

Keywords： biosensor     exosome     cancer diagnosis    

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Glyco-functionalised quantum dots and their progress in cancer diagnosis and treatment

Jayshree Ashree, Qi Wang, Yimin Chao

Frontiers of Chemical Science and Engineering 2020, Volume 14, Issue 3,   Pages 365-377 doi: 10.1007/s11705-019-1863-7

Abstract: breakthroughs in recent years of research, we are still unsuccessful to effectively diagnose and treat cancerThus, the development of a novel approach for cancer detection and treatment is crucial.lectins, Glyco-functionalised QD is a new prospect in constructing biomedical imaging platform for cancerutilisation of Glyco-functionalised QDs as well as their future prospective to interpret and confront cancer

Keywords： carbohydrate     leptin     glyco-functionalised QD     bioimaging     cancer diagnosis and treatment    

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Exploring the diagnosis markers for gallbladder cancer based on clinical data

Lingqiang Zhang,Runchen Miao,Xiude Zhang,Wei Chen,Yanyan Zhou,Ruitao Wang,Ruiyao Zhang,Qing Pang,Xinsen Xu,Chang Liu

Frontiers of Medicine 2015, Volume 9, Issue 3,   Pages 350-355 doi: 10.1007/s11684-015-0402-2

Abstract:

Presently, no effective markers are available to facilitate gallbladder cancer (GBC) diagnosis.This study aims to explore available markers for GBC diagnosis.Additionally, based on the independent risk factors, the GBC diagnosis model was established.Age, TB, ALP, and CA125 can be used as auxiliary diagnosis factors of GBC.The diagnosis model provides a quantitative tool for GBC diagnosis when comprehensively considering various

Keywords： marker     gallbladder cancer     diagnosis    

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Molecular classification of non-small-cell lung cancer: diagnosis, individualized treatment, and prognosis

Yue Yu, Jie He

Frontiers of Medicine 2013, Volume 7, Issue 2,   Pages 157-171 doi: 10.1007/s11684-013-0272-4

Abstract:

Non-small-cell lung cancer (NSCLC) is the most common cause of premature death among the malignantmicroarray technology reported during the past decade, as well as their applications for improving the diagnosis

Keywords： non-small-cell lung cancer     molecular typing     individualized medicine     molecular-targeted therapy     gene expression    

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Design and evaluation of a novel biopsy needle with hemostatic function

Frontiers of Mechanical Engineering 2023, Volume 18, Issue 2, doi: 10.1007/s11465-022-0738-7

Abstract: Biopsy is a method commonly used for early cancer diagnosis.Safer biopsy will result in a more accurate cancer diagnosis and a decrease in the risk of complications

Keywords： cancer diagnosis     biopsy needle     hemostatic function     predictive model     coupled Eulerian−Lagrangian    

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Nanotechnology and Nanomedicine: A Promising Avenue for Lung Cancer Diagnosis and Therapy Review

Wei Yin, Feng Pan, Junjie Zhu, Junwu Xu, Diego Gonzalez-Rivas, Meinoshin Okumura, Zhiyong Tang, Yang Yang,

Engineering 2021, Volume 7, Issue 11,   Pages 1577-1585 doi: 10.1016/j.eng.2020.04.017

Abstract:

Lung cancer is a leading cause of cancer-related death worldwide, with a very poor overall five-yearThe intrinsic limitations associated with the conventional diagnosis and therapeutic strategies usedfor lung cancer have motivated the development of nanotechnology and nanomedicine approaches, in orderto improve early diagnosis rate and develop more effective and safer therapeutic options for lung cancerCancer nanomedicines aim to individualize drug delivery, diagnosis, and therapy by tailoring them to

Keywords： Nanomedicine     Lung cancer     Diagnosis     Therapy    

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Environmental pollution and DNA methylation: carcinogenesis, clinical significance, and practical applications

Yi Cao

Frontiers of Medicine 2015, Volume 9, Issue 3,   Pages 261-274 doi: 10.1007/s11684-015-0406-y

Abstract:

Environmental pollution is one of the main causes of human cancer.Studies on DNA methylation are among the earliest and most conducted epigenetic research linked to cancerFurthermore, prospective applications of DNA methylation to environmental pollution detection and cancer

Keywords： environmental pollution     DNA methylation     cancer     biomarker     diagnosis     therapy     prevention    

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Midline2 is overexpressed and a prognostic indicator in human breast cancer and promotes breast cancer

Frontiers of Medicine 2021, Volume 15, Issue 6,   Pages 942-942 doi: 10.1007/s11684-021-0876-z

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Laboratory diagnosis for malaria in the elimination phase in China: efforts and challenges

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 10-16 doi: 10.1007/s11684-021-0889-7

Abstract: The prompt and precise diagnosis of symptomatic and asymptomatic carriers of Plasmodium parasitesof the China Malaria Elimination Action Plan in 2010, China has formulated clear goals for malaria diagnosisVarious external quality assessments were implemented, and a national malaria diagnosis reference laboratorynetwork was established to strengthen the quality assurance in malaria diagnosis.This review summarizes the lessons about malaria diagnosis in the elimination phase, primarily including

Keywords： malaria     laboratory diagnosis     quality control     malaria elimination     China    

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Tomographic diagnosis of defects in hydraulic concrete structure

ZHAO Mingjie, XU Xibin

Frontiers of Structural and Civil Engineering 2008, Volume 2, Issue 3,   Pages 226-232 doi: 10.1007/s11709-008-0027-5

Abstract: The experimental results indicate that the result of the tomographic diagnosis of a single defect isDefects with the orientation perpendicular to the direction of the diagnosis may have higher precision

Keywords： satisfactory     processing     orientation     tomographic diagnosis     orientation perpendicular    

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convolutional tree-inspired network: a decision-tree-structured neural network for hierarchical fault diagnosis

Frontiers of Mechanical Engineering 2021, Volume 16, Issue 4,   Pages 814-828 doi: 10.1007/s11465-021-0650-6

Abstract: The fault diagnosis of bearings is crucial in ensuring the reliability of rotating machinery.However, the inexplicability and low generalization ability of fault diagnosis models still bar themneural network, that is, the deep convolutional tree-inspired network (DCTN), for the hierarchical fault diagnosisadvantages in 1) the hierarchical structure that can support more accuracy and comprehensive fault diagnosisThe multiclass fault diagnosis case and cross-severity fault diagnosis case are executed on a multicondition

Keywords： bearing     cross-severity fault diagnosis     hierarchical fault diagnosis     convolutional neural network    

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Method for solving the nonlinear inverse problem in gas face seal diagnosis based on surrogate models

Frontiers of Mechanical Engineering 2022, Volume 17, Issue 3, doi: 10.1007/s11465-022-0689-z

Abstract: However, they have not been introduced into gas face seal diagnosis tasks because of the unacceptable

Keywords： surrogate model     gas face seal     fault diagnosis     nonlinear dynamics     tribology    

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Machine learning for fault diagnosis of high-speed train traction systems: A review

Frontiers of Engineering Management doi: 10.1007/s42524-023-0256-2

Abstract: Therefore, performing fault monitoring and diagnosis on the traction system of the HST is necessary.Machine learning has made considerably advancements in traction system fault diagnosis; however, a comprehensiveaims to review the research and application of machine learning in the field of traction system fault diagnosisThen, the research and application of machine learning in traction system fault diagnosis are comprehensivelyFinally, the challenges for accurate fault diagnosis under actual operating conditions are revealed,

Keywords： high-speed train     traction systems     machine learning     fault diagnosis    

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Progress and challenges in RET-targeted cancer therapy

Frontiers of Medicine 2023, Volume 17, Issue 2,   Pages 207-219 doi: 10.1007/s11684-023-0985-y

Abstract: Oncogenic RET fusions or mutations are found most often in non-small cell lung cancer (NSCLC) and inthyroid cancer, but also increasingly in various types of cancers at low rates.

Keywords： pralsetinib     selpercatinib     RET-alteration     lung cancer     thyroid cancer     tumor-agnostic therapy     drug    

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Epithelial-to-mesenchymal transition in cancer: complexity and opportunities

Yun Zhang, Robert A. Weinberg

Frontiers of Medicine 2018, Volume 12, Issue 4,   Pages 361-373 doi: 10.1007/s11684-018-0656-6

Abstract: termed the epithelial-to-mesenchymal transition (EMT) plays an important role in both development and cancerinvasiveness, drug-resistance and the ability to form metastases at distant organs, and thereby contribute to cancer

Keywords： epithelial-to-mesenchymal transition     cancer     metastasis     cancer stem cell    

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Title Author Date Type Operation

Biosensor-based assay of exosome biomarker for early diagnosis of cancer

Journal Article

Glyco-functionalised quantum dots and their progress in cancer diagnosis and treatment

Jayshree Ashree, Qi Wang, Yimin Chao

Journal Article

Exploring the diagnosis markers for gallbladder cancer based on clinical data

Lingqiang Zhang,Runchen Miao,Xiude Zhang,Wei Chen,Yanyan Zhou,Ruitao Wang,Ruiyao Zhang,Qing Pang,Xinsen Xu,Chang Liu

Journal Article

Molecular classification of non-small-cell lung cancer: diagnosis, individualized treatment, and prognosis

Yue Yu, Jie He

Journal Article

Design and evaluation of a novel biopsy needle with hemostatic function

Journal Article

Nanotechnology and Nanomedicine: A Promising Avenue for Lung Cancer Diagnosis and Therapy

Wei Yin, Feng Pan, Junjie Zhu, Junwu Xu, Diego Gonzalez-Rivas, Meinoshin Okumura, Zhiyong Tang, Yang Yang,

Journal Article

Environmental pollution and DNA methylation: carcinogenesis, clinical significance, and practical applications

Yi Cao

Journal Article

Midline2 is overexpressed and a prognostic indicator in human breast cancer and promotes breast cancer

Journal Article

Laboratory diagnosis for malaria in the elimination phase in China: efforts and challenges

Journal Article

Tomographic diagnosis of defects in hydraulic concrete structure

ZHAO Mingjie, XU Xibin

Journal Article

convolutional tree-inspired network: a decision-tree-structured neural network for hierarchical fault diagnosis

Journal Article

Method for solving the nonlinear inverse problem in gas face seal diagnosis based on surrogate models

Journal Article

Machine learning for fault diagnosis of high-speed train traction systems: A review

Journal Article

Progress and challenges in RET-targeted cancer therapy

Journal Article

Epithelial-to-mesenchymal transition in cancer: complexity and opportunities

Yun Zhang, Robert A. Weinberg

Journal Article